The thing that strikes me, is that PwMS are still not being told all the facts. It may be only 1 in 1000 fatalities due to PML, but there were 7 others who died from other infections, after being on Tysabri, and those deaths should certainly be in the count.

So Deaths attributed to T are approx. 3 in 1000 or 1 in 333. That changes the risk factor in a big way, IMO. There are also several who have suffer infections and are still surviving, including one with PML. This should also be part of the deciding factors, to use Tysabri.

There are severeal Neuros just not wanting to take the chance on T with their patients....Maybe they have considered the true statistics/risks here. I applaud their restraint, on behave of their patients.

Remember, this is not a cure and from what I've learned, doesn't just keep the bad T-cells from crossing the blood brain barrier, but also the good, leaving your immune system unable to fight off ANY infection, for some people.