Thread: Imipramine
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Old 04-29-2009, 07:20 PM
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mrsD mrsD is offline
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mrsD mrsD is offline
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Join Date: Aug 2006
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15 yr Member
Lightbulb

It is worth a try. However there are downsides to imipramine.

If you are <cough> elderly....you could have a problem with it.
http://www.mentalhealth.com/drug/p30-t03.html
Quote:
In predisposed and elderly patients, imipramine may, particularly at night, provoke pharmacogenic (delirious) psychoses which disappear without treatment within a few days of withdrawing the drug.
Please read all the warnings on the site I am linking.
At the starting doses of 10mg -25mg it is not such a problem.
Above 25mg a day it may become a problem depending on the person, their age, and cardiac status.

All of the tricyclics are anticholinergic in action. This is why they were replaced by SSRIs. Anticholinergics are hard for elderly patients to handle. When younger, this effect is not present or just very much less. Signs to you will be dry mouth, and blurred vision. Those are the most common effects in the beginning. For males there may be urinary retention.

Tricyclic antidepressants work by increasing serotonin in the brain and do so more slowly than the more modern SSRI types.
This is slower for them, so time is needed to see the effects.

One can try to do this without drugs...by using l-tryptophan and B6 which may help the body synthesize more serotonin that way.
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