I think I posted about this before, but it's worth a repost. Zonegram is also good for nerve pain, like neurontin, another anticonvulsant:

Zonisamide has beneficial effects on Parkinson's disease patients

Miho Murata

Department of Neurology, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan

Neuroscience Research
Volume 41, Issue 4 , 21 December 2001,


Abstract

Zonisamide (ZNS) is a generally well tolerated anticonvulsant that has beneficial effects on Parkinson's disease (PD). ZNS (300 mg/day) given to a patient with PD who incidentally had convulsive attacks, ameliorated the attacks and, surprisingly, his parkinsonian symptoms.

We, therefore, carried out an open trial of ZNS on nine patients with PD. Patients were given 50–200 mg/day ZNS in addition to their anti-PD drugs.

Seven clearly showed lessening of symptoms, especially wearing-off. We speculate that long lasting activation of dopamine synthesis by ZNS ameliorates parkinsonian symptoms, in particular wearing-off.

FULL ARTICLE:

http://www.sciencedirect.com/science...171309c05523b2

FROM ANOTHER ARTICLE:

"Recently, the clinical and experimental studies have suggested some new indications for ZNS administration, as mania, neuropathic pain, Parkinson's disease or migraine prophylaxis. Nowadays, it is also well established that ZNS exerts neuroprotective properties."

http://www.if-pan.krakow.pl/pjp/pdf/2003/5_683.pdf