If giving advice I'd say talk with your doctor, everyone is different and on other different medications...
Having said that, I'm prescribed one every 6 hours max 6/day but my MD is aware that I'm regularly takin on a 4-5 hour schedule during the day...I try to aim 7am, 11am, 3pm, 7pm. If I overdo and the pain is getting out of control I may take 2 (again my MD is aware) or like tonight I'm not sleeping because of pain, I'll take one hoping the pain will lessen enough to sleep.

My RSD is in my right leg, knee down to ankle, following motorcycle accident. I have to keep the pain under control during work hours in order to function. I have 6 1/2 more years until retirement (I hope) if they don't do away with our pension plan. As soon as I get home I'm in bed with my leg up. Lynnie