Yes I do have Alpha-1 antitrypsin deficiency, and having MG my Dr. is using me in his study, big bonus for him, don't think so much for me but hey if the treatment he wants to try helps someone down the road, then what the heck so I am going for it. You are correct on the coffee, I too drink it all the time, so strong that my husband has his own coffee maker..LOL Annie, yes, I get hives and other reactions, to be honest, even when I eat I break out in hives, so needless to say, I don't eat much anymore. Feeling good today I think I will work on my book while I have the energy