I'm new here and lucked onto this site. I was put on mestonin about 2 weeks ago by my neuro. My acetylcholine test came back negative and was through the EMG with upper leg muscles being weak. I have the double vision, droopy eyelids and weak eye muscles. There are days when I'm so fatigued I don't feel like doing anything. My doctor wants me to have a MUSK test. He's positive I have MD and wanted to put me on the drug to see if it helps. I started out with 1/2 a pill twice a day for a week and now am on 1 pill twice a day. Some days my eyes twitch and others they don't. My eyelids are still droopy. I was wondering how long till this mestonin takes to work. I'm suppose to call my neuro after using it 30 days to let him know if it's working or not. When walking up steps it feels like I have cement blocks on my feet. I've noticed the mestonin helps that on some days.