I was taking 1 (60 mg) every 4 hours. My neuro upped it to 2, but I couldn't handle it. My legs hurt so bad, in discussion with my neuro, I have switched to 1.5 tablets every 4 hours. I also get a thick tounge when I need more. My speech becomes garbled, I sound like a drunk.

Other symptoms of too much mestinon:
*with every move I made I thought I was going to pull a hamstring
*my legs were so sore and weak, I felt like I had been lifting weights
*cramps, I got terrible painful cramps in my toes, bottom of my feet, and calves. I also got bad charlie horses in my upper ribs
*my whole body twitched inside, a very strange feeling