I went into a 3 and half week coma and one of the reasons the they think is off of these patches... i would immeditaly call your doctor and tell him what is going on... These things are not a joking matter after my coma my doctor explained that most ppl go into a coma like state and die... if they have to much of the fentanly in there system or if their body simply is reacting to it badly... REALLY I STRESS CALLING YOUR DOCTOR!