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Old 05-20-2009, 02:39 AM
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mrsD mrsD is offline
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mrsD mrsD is offline
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Join Date: Aug 2006
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Posts: 33,508
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Originally Posted by Judy View Post
Okay, the diazapam (Valium), doesn't seem to be helping with the spasms in my legs anymore, so my neuro suggested tinezine (Zanaflex). If that doesn't help, there's another one he mentioned and after that the Baclofen pump. Needless to say, I really don't want to go that route!

The spasms are awful whenever I try to move my legs/feet (hoisting them with my hands). Each leg feels like it weighs 50 lbs. and sticks straight out plus hurts like crazy. If I've been sleeping, my arms and back also spasm. Just started the tinezine (sp?) yesterday at 1/2 a tablet. So far there is no difference except to be constantly sleepy and my vision is blurrier than usual.

So, I was wondering if anyone else has had experience with this, results, etc. Thanks so much friends!

I'd just like to mention to the newbies who might read this, I've probably had MS for 33 years -- before any drugs, not even MRI's so this isn't a definite thing that will happen to you!

Hugs..........
This drug is related to clonidine and shares the effects on blood pressure on about 30% of patients.
So be watchful of standing up suddenly, or feeling faint.
If you have those effects it might be a good idea to monitor your blood pressure at home. A manual BP cuff only costs about $20 and can be very helpful.

In my experience Tizanidine helps with muscle spasms when people are resistant to other drugs. But it is sedating for some as well.

You may benefit from magnesium as well. When this mineral is low, muscle issues become aggravating (cramping/twitching).
There are papers on the net connecting low magnesium status with MS. I just did a quick search...using the keyword "low magnesium multiple sclerosis".

I have a magnesium thread here:
http://neurotalk.psychcentral.com/showthread.php?t=1138

Aim for dosing at 1/2 the RDA to start. Often this is enough for most people.
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