In reflecting further upon the safety issues of Methadone, I realize that I could have been more thoughtful in the initial post at the top of the thread, when I referred to the "Prescribing Information" sheet, to which I then linked.

In retrospect, and as with Opana ER http://www.opana.com/pdf/opana_er_pi.pdf#page=16, I should have referred to fact that Methadone has a "black box" Prescribing Information sheet, so that the reader might be aware that there were potentially significant safety issues associated with the drug, including the possibility of death.

Apologies.