Seems they should be able to make Premarin ,Prempro and Premphase type of hormone replacements some other way by now.
Synthetically or something.


[What is a PMU/Premarin foal or mare?
PMU stands for Pregnant Mare's Urine.
Premarin is a hormone replacement therapy drug (HRTD) given to women during menopause. It is made by extracting estrogen from the urine of pregnant mares. Other HRTDs are made from PMU as well, such as Prempro and Premphase.]