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Old 05-22-2009, 03:21 PM
Lara Lara is offline
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Join Date: Sep 2006
Posts: 10,984
15 yr Member
Lara Lara is offline
Legendary
 
Join Date: Sep 2006
Posts: 10,984
15 yr Member
Default Immunopathogenic mechanisms in tourette syndrome

http://neurotalk.psychcentral.com/post499139-46.html
I already posted this one but I'll leave it here and quote the material regarding T cells.

PubMed
Mov Disord. 2009 Apr 7.
Immunopathogenic mechanisms in tourette syndrome: A critical review.
Martino D, Dale RC, Gilbert DL, Giovannoni G, Leckman JF.

Department of Neurological and Psychiatric Sciences, University of Bari, Bari, Italy.

<snipped abstract>
Quote:
Finally, a general predisposition to autoimmune responses in TS patients is indicated by the reduced frequency of regulatory T cells, which induce tolerance towards self-antigens. Although the pathogenic role of immune activation in TS has not been definitively proven, a pathophysiological model is proposed to explain the possible effect of immunity upon dopamine transmission regulation and the generation of tics.

Last edited by Lara; 05-22-2009 at 03:53 PM.
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