PubMed
Biol Psychiatry. 2007 Feb 1;61(3):273-8. Epub 2006 Sep 25.
Decreased numbers of regulatory T cells suggest impaired immune tolerance in children with tourette syndrome: a preliminary study.
Kawikova I, Leckman JF, Kronig H, Katsovich L, Bessen DE, Ghebremichael M, Bothwell AL.
Department of Immunobiology, Yale School of Medicine, New Haven, Connecticut
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CONCLUSIONS: These data support our hypothesis that at least some TS patients may have a decreased capacity to inhibit autoreactive lymphocytes through a deficit in T reg cells. Interactions of host T cell immunity and microbial factors may also contribute to the pathogenesis of TS.
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http://linkinghub.elsevier.com/retri...06322306008043