I on the other hand do feel that my swelling in my ankles and feet which occurs year round but especially in the heat is caused by my PN. I never had swelling in my ankles or feet before. My circulation is good as evidenced by sonogram and blood pressure checks in ankles. I have tried water pills but they do nothing. My feet are very numb and i think that the electrical signal needed to set in motion the process to remove fluids in the feet is very weak and in the heat that signal slows down further. It doesnt matter if i am on my feet or not, they swell.