I think it is unique to each person's ability to handle the purines.
Tissue destruction also releases purines.
People undergoing chemo for various leukemias, often develop gout as
the blood cells die. It is very common to see allopurinol then, for
the secondary gout. (this differs from inherited gout, where the enzyme is
faulty.
One thing poorly understood is why one can have a high uric acid reading,
with no symptoms. What triggers the actual attack has not been fully
researched yet.
BTW a woman discovered the drug allopurinol (Zyloprim).. she was a biochemist
at Burroughs/Wellcome --now called GlaxoSmithKline. It was a metabolite
of mercaptopurine I believe.
http://inventors.about.com/library/i...rs/blelion.htm
and a picture:
http://www.achievement.org/autodoc/page/eli0pro-1
http://www.chemistry.org/portal/a/c/...944fd8fe800100
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei
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Weezie looking at petunias 8.25.2017
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