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Originally Posted by rose
It has been over 30 years since proven that about 1% of large doses of B12 (even the worst form) will be absorbed by those with the most severe malabsorption. Since then it has been shown (to the satisfaction of some very good medical textbooks) that daily oral doses of 1000 - 2000 mcg is as good or better for most with severe malabsorption.
One who is taking methylcobalamin will do even better. And, of course, in that case many times more can be taken with total safety.
Dissolve, chew, or swallow.
rose
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In the case of people with pernicious anemia if either the common B12 or Methylcobalamin is swallowed rather than dissolved under the tongue,
none will get into the system for want of intrinsic factor.