You sound like you definitely need to be checked for gluten intolerance, your sister too. Thing is, unless you have celiac disease, they can't tell if you are gluten intolerant, only by testing the waters, meaning, after being tested for celiac, if you get a negative response, then you should try the gluten free diet. There is no test for gluten intolerance, not really. I am gluten intolerant, some doctors tell me I am not celiac, others say I am. My blood work says "double DQ1 genes" which are gluten intolerant genes. I have been gluten free for nearly 9 yrs. I too, have neuropathy, which I'm sure was caused by all my years of malnorishment because of gluten in my system. I also had terrible anxiety, and panic attacks. First I was on Xanax, then Paxil, for years before going gluten free. To this day, I keep Xanax on hand for bad days.

Your PCP can have you tested, of you could go for a specialist, such as a gastro doc. Do not take no for an answer, don't let them say, "You don't look celiac." There is not really a look about us, I gained weight when I was malnourished, my sister lost. My sister is a diagnosed celiac, and our dad is gluten free, she for 9 yrs, he for 4 1/2 yrs. They should do testing for Gliadin levels, being IGA, and IGG, along with HLA typing, for celiac disease. You should also have your B12 level checked and your Vit D level.

As for fatigue, I also have chronic fatigue, because of high Epstein Barr Virus levels. It's difficult having fatigue. I also am diagnosed with sleep apnea, and on CPAP. With chronic fatigue, the general RX is rest and exercise. With celiac disease/gluten intolerance, the RX is a gluten free lifestyle, totally gluten free.