We have seen several reports that coffee has a protective effect on warding off PD. For example http://www.gairrhydd.com/features/sc...ell-the-coffee
states, "Another study comparing heavy coffee drinkers (3.5 cups a day) with non-drinkers found that the coffee drinkers were significantly less likely to contract Parkinson’s Disease later in life. Likewise, a second study found an inverse relationship between the amount of coffee regularly drunk and the likelihood of developing Parkinson’s Disease."
This is another one to add to the list of beneficial substances which reduce the permeabilty of the BBB.
http://www.mombu.com/medicine/allerg...n-2470596.html
states, " A study in the open access publication, Journal of
Neuroinflammation revealed that caffeine equivalent to just one cup of
coffee a day could protect the blood-brain barrier (BBB) from damage
that occurred with a high-fat diet."
Also,
"In this study, researchers from the University of North Dakota School of
Medicine and Health Sciences gave rabbits 3 mg caffeine each day -- the
equivalent of a daily cup of coffee for an average-sized person. ...After 12 weeks a number of laboratory tests showed that the BBB was
significantly more intact in rabbits receiving a daily dose of caffeine."

Yet I can't interest any researchers or organisation to take seriously the involvement of a defective BBB in PD. How many more need we add to the list.
Ron