If you want to get really depressed go to an archive such as PIENO (?) with posts back to the mid-90s with people just like us saying similar things and being told the same pablum. Those folks are dead and if nothing changes some poor soul is going to be reading these posts in fifteen years with the same despair.

The vast majority of the time decisions are made in the organism's self interest. This is true of bacteria, PWP, scientists, and orgs. It often is unconscious and often well intentioned, but down at the core the survival of self comes first. The interests of PWP demand speed. The interests of researchers demand methodical (read "slow") repetitive work. Orgs have their own interests and those of investors are plain.

Four different and competing interests. If PWP get the cure they need, the other three are history. This triad is in charge. They control the money and the debate. We PWP play nice until we are too bad off to do much.

What to do? The only thing I can think of is to warn the Noobs and radicalize them now while they can show up out in the halls with cream pies.