Would the slow release vs the reg be different possibly for you in reaction? You stated flexeril but I am on klonopin and that is supposed to help with muscle relaxing and also to help with sleep. For me not much of a change but have heard others be helped. Lastly I have a sensitive stomach and took many of those meds with a glass of milk as it is supposed to coat the stomach. I do know with Cymbalta for 2 weeks I was over a toilet or with a bucket but then it wore off but no help with the pain. Why can't there be happy side effects? Most frustrating is when the original pain is there plus the side effects. I hope you get some relief asap.