hi all
this is one of my threads from another forum regarding repairing the dura matter but the principle I would imagine is the same for neurons

my, musing on this subject

http://www.uic.edu/depts/dort/tissuelab.html


Autologous Stem-Cell within the cerium spinal sytem are composed of the following cell and stem cell types osteoblasts, adipocytes, chondrocytes, neurons, myocytes, and tenocytes stem cells are the maintenance crews, they can self replicate I will try to describe there function

osteoblasts....

A specialized bone cell that produces and deposits the matrix that is needed for the development of new bone and consists primarily of collagen fibers. Osteoblasts are formed from osteoclasts on the outer surfaces of bone and in bone cavities, and bone deposition takes place constantly in living bone. As new bone grows and hardens with the addition of calcium and phosphate, osteoblasts become embedded in the bone matrix and develop into osteocytes

adipocytes

fat cell a soft greasy substance occurring in organic tissue and consisting of a mixture of lipids

Chondrocytes


(from Greek chondros cartilage + kytos cell) are the only cells found in cartilage. They produce and maintain the cartilaginous matrix, which consists mainly of collagen and proteoglycans. Although chondroblast is still commonly used to describe an immature chondrocyte, use of the term is discouraged, for it is technically inaccurate, since the progenitor of chondrocytes (which are mesenchymal stem cells) can also differentiate into osteoblasts

Neurons

(also known as neurones and nerve cells) are electrically excitable cells in the nervous system that process and transmit information. In vertebrate animals, neurons are the core components of the brain, spinal cord and peripheral nerves.

myocyte,


is a single cell of a muscle. Muscle fibers contain many myofibrils, the contractile unit of muscles. Muscle fibres are very long; a single fibre can reach a length of 30cm.

tenocytes

A tendon (or sinew) is a tough band of fibrous connective tissue that usually connects muscle to bone[1] and is capable of withstanding tension. Tendons are similar to ligaments except that ligaments join one bone to another. Tendons and muscles work together and can only exert a pulling force.

now we have found that CSF is caustic to bone and tissue ?
and will quickly break down blood cells, so what is the dura mater lining consist off ???

mesothelial

cells lining the inner part of the dura mesothelial

or a specialized type of mesothelial( mesenchymal stem cells??? ) I do not see this type off stem cell in the list of Autologous Stem-Cell that have been isolated yet ? now, I would muse that it is only these type of stem cell that would be of use as a dural patch ?

I would like to see that a mixture, of the different types of stem cells would migrate to the matrices, seeded with each type of cell in vitro and inviro ?

in connective tissue problems in the outer dura mater and skeletal muscular area surrounding the leak site I would imagine would benefit from and injection of healthy stem cells of the required type

If the person has genetically faulty
Autologous Stem-Cell this will be a more complex issue within the bone marrow its self ?

I have used the word mussing because this is just my thoughts and may not have a basis in fact but I thought I would share them