Hello. My husband was diagnosed with anti MAG peripheral neuropathy on May 12, 2009. His anti MAG count is 110,000. He begain having symptom 2 years ago, starting with numbness in his toes on his right foot. He now has numbness and weakness in his toes, foot, and ankle on his right side and is beginning to have numbness in his toes on his left side. We are seeing his neurologist again on July 14 to discuss treatment with rituxan. We have read about its side effects, effectiveness, and high costs. We would like to hear from anyone who has experience with this illness. Does it always progess to wheelchair confinement and, if so, in what timeframe? Is it better to have treatment earlier or later? We appreciate your feedback. Thank you.