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Old 06-26-2009, 12:50 PM
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mrsD mrsD is offline
Wisest Elder Ever
 
Join Date: Aug 2006
Location: Great Lakes
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15 yr Member
mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

Look at this new drug.... NOT EVEN INSULIN and it lowers morning fasting levels:

Cycloset:
http://diabetes.webmd.com/news/20090...loset-approved

Also they are going to do studies with Melatonin and
Type II... since finding the melatonin receptors in the pancreas.

People who are not making enough melatonin, may have higher blood sugars!

I've noticed since I have aged and moved closer to diabetes, that I get really hungry at night now...around 4am. 90% of the time I ignore it...but once in a while I will cave in and have some cereal (unsugared). I think at 4am I am hypo, and then my liver starts converting glycogen to sugar and by the time I get that fasting done, it has gone up. (this is why metformin works so well...it prevents gluconeogenesis by the liver!) The only other time in my life that I got hungry at 4am was when I was pregnant.

So there may be a component of altering the circadian rhythm
changing blood glucose levels. The morning high might just be a survival thing, so we can get going properly.
So far the medical community focuses on insulin to treat diabetes, and now that is changing too!
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