The reason they tell people with CFS to take antioxidants daily is because people with CFS are flooded with oxidants and your antioxidant reserves are depleted either from undermethylation, infection or from excess NO2 (Nitric Oxide).

When you start the methylation process that infection that is lingering in your body and unable to get out will start to be removed, you might get detox reactions and start feeling worse than you do but in time you will get better and back to normal.

The HPA axis (Hypothalamic-Pituitary-Adrenal) Is another trigger in CFS. Since in some people due to extreme daily stress their body's internal biochemistry has just cracked or broken if you will. Even bioloigcal stress such as malnutrition/undernourishment of nutrients and low thyroid hormones etc will cause this.


What can be done is:

1. Complete hormone testing (genova has a female and male hormone profile) - getting hormones into range will be key

2. Nutritional evaluation - through ONE test at genova, a hair mineral analysis is also useful to detect any heavy metal overload.

3. Saliva Cortisol profile + DHEA's 4x throughout the day. So this is a saliva tube you spit into at four different times during the day. 6am, 12pm, 6pm, 10pm. This shows you where your cortisol levels are either high or low. Most people with CFS have low cortisol particularly in the morning and feel like zombies in the morning since you need enough cortisol in the morning to get going. If you do show low cortisol you can start on something like Isocort to increase cortisol levels. If on the other hand you have high cortisol a supplement such as Phospholydlserine can be used to reduce levels.

4. Avoiding wheat, dairy and soy if you're not already doing so, which tend to be common hidden allergens in many people.

5. GI Effects Stool Profile from Metametrix this has DNA analysis also, this is the worlds best stool testing. This test is excellent at evaluation gastrointestinal function. You need to be able to absorb your food to create energy you need everyday thats why most people with CFS have a problem with their digestion. This test evaluates - parasites, worms, yeasts, digestion, absorbtion, beneficial bacteria and coeliac disease/gluten intolerance.