ya they work,,,i take them when i need them,they calmed my legs down and they arent red very much anymore,,my neuro dr and painmanage dr both put me on them,,the loading phase is what sucked,,thought i was losing it,,,but i found a my groove with tghem,,i take 3 or less per day now that ive got a scrip of them,,,too may and im moody,,,..but they do what the dr said they do,,bobber also the nurse said that men due to the testosterone,,makes them a little more whacked until your body gets used to them,,and i also take a break from them too,,that way i skip the long term effects