Dr. Atamna, who was one of the authors of the 2008 MB study in Oakland that was cited earlier here on NT, has moved on to the Commonwealth Medical College in Pennsylvania.

His lab is very focused on aging with a particular emphasis on the mitochondria, and on the website of Commonwealth his research work is listed. Here's the website link to his research areas:

http://www.thecommonwealthmedical.co...geID=OTH000232

Here's the snippet related to MB, which I found very encouraging as he (briefly) discusses follow-up work to that he did when he was at Oakland and did the MB study funded by Dr. Bruce Ames:

"New, safe, and potent anti aging drug;
Follow up research in this direction in my lab has identified an additional class of anti-aging agents; the diaminophenothiazines. Methylene blue (MB) is the most active and relevant to human. MB protects mitochondria in vivo and in vitro at efficiency that exceeded NtBHA by 1000 folds. This new class of anti-aging agents reversed the decline in cognitive performance and muscle strength in old mice. My lab is investigating the mechanism of action of these agents. Based on the experimental results, I believe that these agents participate in oxidation-reduction reactions at the level of the mitochondrial electron transport chain (e.g. complex I & IV). This interaction prevents the formation of superoxide radicals, protects the mitochondria from oxidative damage, and promotes mitochondrial biogenesis.
Our eventual goal is to use these agents to prevent the production of free radicals and the mitochondrial dysfunction associated with age-related disabilities. My lab currently is actively searching for nutriceutical that may mimic the action of these drugs. We have made a humble success in this direction."

Thoughts?