Have been on Savella for 5 weeks. First 2 weeks were great on the titration pack, lots of energy and no pain, but as soon as I had RX filled ($30.00 with ins.) within 3 days side effects began. Insomnia and headaches. Have been dealing with this for about 3 weeks and have missed 12 or 13 days of work due to the fatigue and headaches. Spoke to Drs. office today about how to wean off. Looks like this one will not work for me either. Already tried Cymbalta (crazy) and Lyrica (swelling and no pain relief).