Carrie, I haven't been on for awhile - not feeling well. But I wanted to say that I hope you will ask your primary doctor to make sure you don't have any electrolytes that are off that could make your muscles cramp up. Or thyroid either. And it's hard to know if you are taking too much or not enough Mestinon. When you are off of it, in between doses, does the cramping get better or worse? If it gets better, you might be taking too much. If it gets worse, you may need more. I just wanted to make sure you are checking all possibilities. Take care.

Annie

I take 90 mg. every 3 hours, round the clock.

PS - Do you take vitamin D and calcium?