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Old 07-06-2009, 01:55 PM
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mrsD mrsD is offline
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Join Date: Aug 2006
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mrsD mrsD is offline
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mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Question

Quote:
Originally Posted by stagger View Post
Thanks for posting this drug,
After reading about Elavil in this forum I naturally want to give it a try. Here are some limitations I have found, I'm on methadone and Lyrica and my methadone information sheet forbids the use of amitriplyine with methadone. I have been on Lyrica for four years and was on very high doses with Tramadol and developed breathing problems plus I fell a lot more than I do now. Also have developed a neuroma in my right foot and a knot on the back of my neck. Studies had shown that Lyrica caused tumors in rats when it was being tested. If all I had to take is amitriplyne for pain relief that would be just GREAT. After 2 years on Proscar and double dosages of Flomax I had the TURP surgery performed the 15th of May. The only problem was withdrawl on the second day as they did not allow me methadone and Lyrica for my PN pain. What is the recommended starting dosage of Elavil. Thanks
If you are still planning on using the methadone, Elavil could be problematic. It would all depend on your EKG and whether you show long QT tendencies. You would have to watch for low potassium and low magnesium also if you combined them.

Most PNs start at 10 or 25mg at bedtime. A few may go up to 50mg at bedtime. In this country they typically don't go higher.
I seem to recall that Brian took fairly high doses.

I think this article is interesting showing actions at the peripheral nerve locations, when all along doctors thought
it was only working centrally in the brain.

If your doctor is younger... he/she may be brainwashed by the SSRI salesforce which painted a dangerous picture for the TCA family .... in the days of depression, very high doses were used, daily of Elavil and its cousins, and suicide attempts were often deadly. One of the salespitches for Prozac when it came out was that it was "safe" in OD scenarios. I attended a psychiatric conference where this was reiterated several times back then.
So some doctors are now of the belief that TCAs are deadly.
They only are in overdose or when mixed into long QT scenarios with other drugs like methadone, etc.

Men with prostate issues may have problems with the anticholinergic aspects of Elavil...they can cause urinary retention. Do you have that still? Or did the surgery fix that?
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