They started me on 100mg 3 times a day,,my wife had been on 300mg 3times a day,,,,it depends on the individual,,, everyone reacts diffent your body will allow you to increase over time,,,i was floored with a 300mg,, its better to start out low,,you can always add,,but you cant take away,,,,im sensitive to all meds,ive had liver problems which makes me hyper sensitive,,,,good luck ,,,, bobber