Dejibo,
I go for my 5th infusion on Monday. PML doesn't scare me. I know it is a possibility, but this disease scares me more. I was on copaxone for 7 months and continued to have relapses, never fully recovering from a post partum relapse that took away so much from me. My symptoms have not improved (yet!!) with Tysabri, but I have not gotten any worse as I was on Copaxone.

I have had zero side effects with tysabri. I'm sleepy for a few days after, but nothing else.

I think tysabri is our best hope in slowing down progression until something else comes along. I have to believe that. Good luck with your decision. I need to tell you that your advice really helped me with the first few difficult months with copaxone. For me, tysabri is a breeze in comparison!