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Old 07-20-2009, 06:49 PM
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reverett123 reverett123 is offline
In Remembrance
 
Join Date: Aug 2006
Posts: 3,772
15 yr Member
reverett123 reverett123 is offline
In Remembrance
reverett123's Avatar
 
Join Date: Aug 2006
Posts: 3,772
15 yr Member
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<snippets>
The MP seems to work by retricting the level of vitamin D in the body.

levels of 25-D over 20 ng/ml can bind and inactivate the VDR, which subsequently shuts down the innate immune system"
<end>

If I understand this right, the MP restricts Vit D. The result would be continued activity of the innate immune system.

Since the big problem in PD seems to be an overactive innate system, it would seem counter-intuitive (i.e. "dumb" ) to promote "continued activity".

The opposite would be true if one were after a hidden pathogen, which is what I remember the MP being about. And it may be just dandy for that. But for auto-immunity something doesn't fit.
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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