Hi, Alan. Do you know if your docs figured out "which" white blood cells are elevated? Here is an explanation of white blood cells for you. Sometimes a doctor can figure out what might be going on if only one "type" of white blood cell is increased.

http://www.nlm.nih.gov/medlineplus/e...cle/003643.htm

Imuran can cause liver problems in someone who lacks the enzyme thiopurine S-methyltransferase (TPMT). People who lack that enzyme can have Imuran build up in their bodies and become toxic. If your doctor is good, they should test for that BEFORE someone starts Imuran.

http://dailymed.nlm.nih.gov/dailymed...fo.cfm?id=9906

It's usually pretty odd for someone who is being "immunosuppressed" to have an increase in white or red blood cells. If it were me, I'd go see a hematologist for a second opinion on it. They are the "blood" experts. I'm not saying you could have cancer, but I know that's what people usually think about when they have a high white blood cell count. There are a lot of reasons it could be high. But you need an expert to tell you for sure if it's a drug reaction (like an allergic reaction) or whatever else it might be.

That's nice of you, Erin, but I'm no expert! Just been around the block too many times and read a lot.

Annie