I used to take hormones as birth control in my younger years and it never affected my mood. They want to make sure I am NOT pregnant when they go to do the surgeries. I have never had Depo before so I just hope it's okay. I really am doing better but I am still pretty emotional about all this. Just not as heavily intensely feeling it like I was before the buspar. The physical symptoms of anxiety were knocking me on my butt and the buspar helps keep that at bay. Thank God for it.