As the others have said, I also feel your discouragement. It seems we with spms are pretty much hung out to dry until they get a better handle on this disease......but........there's always hope! That miracle just might come along when nobody is expecting it!!! All I can say is, keep reading about new trials, etc., but try not to pin all your hopes on each one. Guess it's better they find out it doesn't work or has a problem before they use us as their guinea pigs!!!!

Kicker -- What is 4-ap? Was reading about someone trying it on an MS board from England, but don't know what it is other than it has to be compounded. It's not LDN, is it?

Hang in there!!!!