Hi Jane, Yes I still have symptoms and as was stated here, even though my serum levels have gone way up, the damage was done for many years; maybe decades. Nerve damage is slow to hearl, if at all. My neurologist said that what might happen is that over time I just learn to compensate - in other words I'll never be the same. But that's ok, I'm still hoping for the best! Good luck to you, Jane, and keep your chin up!