Hi, I am currently recieving plasma exchange and have been for 4 months now. Istarted with a run fo 8 days in a row and then continued with 1-2 sessions per week. Fortunately Ihave good veins which I believe is half the battle-makes things a lot easier and process runs smoother. The veins in my arms are used and I only require a peripheral line-those used in IVIG and a fistula to remove the blood. Both these are removed at the end of each session but of course this can be different for everyone. I recieve 2L of plasma based on my height and weight and the mg and normally it can take between 1.5-2 hrs. The only side effects I have experienced have been low calcium levels in which you experience tingling in lips hands feet and cramps and low blood pressure. A calcium supplement normally resolves this or in my case 2 cups of milky hot choc! I have the treatment on an outpatient basis as though my mg is bad at moment I am stable. The decision on where you have it will depend on how bad your mg is. A word of advice if having it on an outpatient basis take any meds at least 2 hours before as the process clears any meds from your blood and if for example your treatment takes one hour take mestinon 3 hours before start of treatment so that you can take a mestinon straight after as I have always felt weaker straight after treatment. The treatment normally takes it out of me for the rest of the day and sometimes the day after. The doctors and nurses will go through this all with you and you won't know how it will effect you until you have it, we all react differently and a nurse will be with you throughout the exchange. As a mother of a 2 year old I actually look forward to it, for me its 2 hours of relaxation with a good book!