I had RLS symptoms when B12 deficient.

Yes, I remember people discussing that any neurological symptoms could worsen if under stress (including not enough sleep, illness, emotional stress). My experience was the same. Also, some days there would be symptoms, and some days I'd be symptom free.

The worsening after shots could be healing... I distinctly remember that I would get worsening symptoms when I took 2000mcg daily instead of 1000mcg daily... and I took that as a positive sign that nerves were healing. I did get better!

Could be the potassium thing, too. My daughter was very twitchy when low potassium. Not just legs though... all over.