So sorry to hear about your problems with plasma exchange.

I take propantheline 15mg x 2 with every dose of mestinon. It stops my stomach feeling like its being ripped apart with a knife, but I still get bowel spasms due to the mestinon. I take loperimide also which helps calm down the stomach cramps and the runs. Although some days despite taking this I still react badly to mestinon. Thats why I have to laugh when Drs say I dont respond to it.......why would I put myself through this if it didn't work?

Love
Rach