There have been some studies to show using acid blocking drugs MAY help prevent damage from NSAIDs like Motrin etc.
They are often given with really potent NSAIDs like Indocin (indomethacin).
But one should not rely on this effect 100%... it is only a suggestion.
The damage from NSAIDs on the GI lining is a systemic effect, not a local one. So local agents are limited in effectiveness. I suspect the makers of the proton pump inhibitors have funded these studies...to increase use of their drugs. But that is only my opinion and reflects some others over time as well. NSAIDs block cox-2 enzymes in the cells lining the GI tract... these Cox 2 enzymes protect the GI lining from damage. When this is blocked, then the lining may become more fragile etc. This effect comes thru the blood stream to the cells and not completely thru the GI contents.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei
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Weezie looking at petunias 8.25.2017
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