Hello again, I posted a couple of times last year...

I'm from the UK, 37 and was diagnosed about a year ago. Main symptoms are a head tremor, tremor and stiffness/slowness in the right hand.

I've been using the patch since July last year in conjunction with Azilect.

I found that initially I had a very positive response - able to wiggle my fingers and the tremor became much less likely to "poke through". But I've found that to maintain the positive effects I've had to titrate up every month or so - past the maximum licensed dose of 8mg to 10mg (with my neurologist's approval). Which has worried me somewhat! We're now discussing a switch to Requip.

Generally I haven't had significant side effects, except I'm slightly more likely to fall asleep on the sofa watching rubbish on TV... Skin reactions have been minimal, except on my belly, where I get unbearable itching within a few hours (the skin is stretched rather thin there though!)

Do other people find that there is a general wearing off or getting accustomed to agonists? Or am I experiencing a placebo effect? Or am I deteriorating as fast as I'm upping the dose?!

So far I've been on 10mg for about a month and am doing OK.

Happy New Year to you all!