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Old 08-23-2009, 06:11 PM
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mrsD mrsD is offline
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Join Date: Aug 2006
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mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
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I found this article on ACE cough fairly interesting: If you cannot read the whole article, you can join for free, anytime.

http://www.medscape.com/viewarticle/484537_2
Quote:
Treatment of Angiotensin-Converting Enzyme Inhibitor Cough

In cases in which the continuation of an ACE inhibitor is necessary despite cough, cromolyn, baclofen, theophylline, and local anesthetics have been reported to be of benefit, although none has been subjected to large-scale trials.[12-14] Although no large, controlled studies have demonstrated the inhibition of ACE inhibitor cough with cyclooxygenase inhibitors, sulindac has been reported to be of benefit, and two studies suggested that intermediate doses of aspirin (500 mg/day) but not low doses (100 mg/day) can suppress ACE inhibitor cough.[15-17] In a small series, Lee et al.[18] tested the hypothesis that because NO has proinflammatory effects on bronchial epithelial cells, supplemental iron, an inhibitor of NO synthase, may reduce the cough associated with the use of ACE inhibitors. Patients treated with iron, but not placebo, had significant reductions in cough scores.
The recommended interventions still leave something to be desired IMO. Not everyone can take iron, or 500mg of aspirin a day.

Here is more information on iron use for ACE cough:
http://www.sciencedaily.com/releases...0817081843.htm
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"Thanks for this!" says:
DizzyLizzy (08-23-2009), ewizabeth (08-23-2009)