Hi,
I get burning sensations in my toes and any other part of my foot which goes numb easily, like my heels, particularly if there is sustained pressure on them.
I did notice that you thought there may be a hereditary factor with your PN, ie HMSN, CMT or possibly HNPP.
High doses of vitB6 are thought to be toxic to HMSN compromised nerves, there is a medical alert on the CMTA website which lists all Medications and Supplements which are considered potentially toxic,
Unfortunately I can't give you the link, because I haven't posted often enough...
If you google for "CMT medical alert" you should be able to find the page