Congratulations to you Mom, for having your two kids in college. That is great.
Time for their Independence, even though your daughter started last year. I know it is hard not having the kids around, like when they were in high school, but you will get used to it. Plenty of phone calls and wash brought home.
Your DS is close by, but needs to be on his own. Girls seem to mature faster than the guys do, IMO.
Are you alone completely or is there someone else at home?