While many gastroenterologists believe that only peopel with HLA-DQ2 or DQ8 genetic profile are predisposed to developing celiac, there are some researchers, notably Dr. Hadjivassiliou, who think that the DQ1 genetic profile is often present in those who suffer neurological symptoms from gluten sensitivity, often without intestinal symptoms (no "frank Celiac") and whose only serological evidence may be an elevated anti-gliadin reading.

More can be found on this in Cara's Gluten File (which is in the Useful Websites section at the top of this forum).