View Single Post
Old 08-31-2009, 03:36 PM
mrsD's Avatar
mrsD mrsD is offline
Wisest Elder Ever
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

Thanks, fmichael.

A little history:
Phenoxybenzamine (Dibenzyline oral) has been on the market for decades. It was originally for hard to control blood pressure in the 70' and 80's. Then it was reduced to use in people with a rare adrenergic tumor of the adrenals called pheochromocytoma.
It was only used for a short time until the surgery removed the tumor.
Here is the RXlist.com monograph
http://www.rxlist.com/dibenzyline-drug.htm

It is very rarely used today. I hadn't dispensed it in 20 yrs easily.

There is another paper on PubMed from Japan, that only used
nifedipine in a patient who developed RSD following renal surgery. So nifedipine might be useful alone, if done correctly at the right dose for the right time frame, and perhaps earlier in the course of the RSD presentation.

I have seen since I did those searches a while back last spring that Dr. H....does list calcium channel blockers in his book..it was a Google book reference I believe, but I didn't save it.

Nifedipine is a fast acting calcium channel blocker and is also used to block premature labor now for pregnant women. It is less used for long term blood pressure control because it can cause gum overgrowth and has significant side effects. Its brand name was ProCardia. Some ERs still use it for toxic hypertension, where a liquid capsule is opened and put under the tongue. That is an emergency use. It is also used, as well as its cousin to treat migraine, in refractory cases.

Here is a wiki article with a list of the family:
http://en.wikipedia.org/wiki/Calcium_channel_blocker

I'll share this with you. If I had RSD and was suffering like the posters I read here, I'd be very aggressive and seek this treatment. I think it is just that not many doctors even know about RSD...and waiting is critical for success with calcium channel blockers. But even a 40% success rate...that is pretty good. We don't have that number at all on Peripheral Neuropathy!
__________________
All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei

************************************

.
Weezie looking at petunias 8.25.2017


****************************
These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.
mrsD is offline   Reply With QuoteReply With Quote
"Thanks for this!" says:
Dew58 (09-02-2009), Sandel (09-03-2009)