I know! I can't believe it is #15. Time flies by quickly. Yes, I definitely think slowing down the infusion has helped significantly. The worst effects I ever got were when the old nurse ran the infusion over 45 minutes. I was sick as a dog in bed for 4-5 days--headache, muscle aches, nausea, flu-like stuff. The whole thing is so strange because in the beginning I didn't always have intense side effects--or at least not every infusion. And then some infusions are more tolerable than others but overall they are better since it has been slowed down. This time I drank a LOT of water and went in very hydrated. I think over time you start to figure out your body and its reaction to the drug, just like you (RW) had the pinpoint itching for awhile and came up with a solution.

I think more doctors should suggest slowing down the infusion if people are having any side effects. I was looking through the Tysabri site on www.thisisms.com and I was amazed at the number of people who have had issues -- nothing overwhelming but enough such that I wouldn't say all people going on Ty. should expect a free ride. Nausea, headaches, and dizziness/cog. fog for a few days seemed to be a problem, especially in the beginning months.

I have always been hyper sensitive to medications of all kinds. If I feel crummy for 1 or 2 days a month then it is worth it to me. I certainly couldn't tolerate the Rebif or Copaxone.

Have a good weekend everyone!