I'm sorry but I don't have problems with Mestinon and GI issues; probably because I don't have stomach acid.

I take Mestinon Syrup. It's cumbersome because the bottles are so big but I don't go out much and have it in a small bottle when I do. What I like about it is that it absorbs more quickly because it's a liquid and I can titrate the doses for how I'm doing (down or up, according to what my neuro has said).

I wish I had more info for you. I hope something will help you soon. It must be scary to have gone through all that and still not be doing well.

Annie