I would ask for a blood test to check your liver if you are getting the bruising. Could very well be the Beta. I would think anything that makes you feel like you have the flu kind of drains the life right out of you.

I have been exhausted since I started Avonex. But I am fatigued with insomnia. I wakeup around 3:30 every morning and that is after a tramadol and ambien to help get me to sleep. I did find I cannot take the shot at night time, or I wake up in the middle of the night freezing/shivering and sick as can be. If I take it during the day and take tylenol every 4 hours and benedryl every 6, it doesn't do anything but make me sleepy.