Niki, as you know I was on ketamine for a very long time , every two months up to the coma and then the whole start up agian, two weeks, monthly then back to my monthly schedule for a week. This went on from 2005 until 2008. I was hospitalized on three major occasions to get 10 pounds then 13 pounds of fluid either out of my legs or off my back. Yes it was edema, but my bladder was not working either. now that i do not have the infusions, my edema has decreased, I do however take a water pill to encourge my bladder to empty other wise I would have major problems still. It is HCL- it blocks calcium to the kidneys. Now unfortunately when I go in - i'm there for a half hour, but i have no feeling of my bladder emptying. Just the urge to go, I do belivie it is from years of ketamine infusions. but i dont know for sure.cz